What is Intrauterine Insemination (IUI)?
Intrauterine Insemination, or IUI, is a type of fertility treatment that involves placing sperm into the uterus. This increases the number of swimming sperm which, in turn, increases the opportunity for a sperm to find the egg.
An IUI is a painless and quick procedure that's often performed in-office by one of our highly skilled nurses. The procedure takes 1-2 minutes to perform and, after a short rest in the office, you’re free to return to normal activities.
Learn More About Intrauterine Insemination (IUI)
IUI Process
This quick and painless procedure takes 1-2 minutes to perform. the IUI itself is usually less uncomfortable than getting a Pap Smear.
This quick and painless procedure takes 1-2 minutes to perform. the IUI itself is usually less uncomfortable than getting a Pap Smear.
- We will ask you to come to the appointment with a full bladder to optimize the angle between your uterus and cervix
- Before placement, the semen sample must be washed and prepared
- A small, flexible catheter will be passed into the uterine cavity
- Afterwards, you’ll have a short rest in the office and then you’re free to return to your normal activities.
Why Sperm is Washed Prior to Placement
Washing the semen sample has many benefits:
- Improves sperm motility: washing activates the sperm and removes substances that might lower sperm quality
- Helps identify the most actively swimming sperm
- Removes Prostaglandins: Prostaglandins are proteins found in semen that can cause violent uterine contractions if placed inside your uterus
Intrauterine Insemination (IUI) FAQ
While IUI places sperm directly in the uterus, the sperm still needs to swim to the egg. Because of this, we recommend IUI for a sperm count of at least 7 million total motile sperm.
Women under 35: a 10-20% chance of pregnancy after each IUI
Women over 35: a 2-5% chance of pregnancy after each IUI
In addition, IUI has a cumulative success rate. This means the highest chance of pregnancy for many women is around 3 to 4 cycles.
If an IUI is successful, human chorionic gonadotropin (hCG) can be detected in the blood or urine after 2 weeks. At this time, you can take a pregnancy test to determine if the IUI was successful.
In IVF, the egg is extracted from a woman, combined with sperm, and then placed back into the uterus. In IUI, the sperm is placed directly into the uterus.